A nationwide study of RDI in CHOP-like chemotherapies in patients with non-Hodgkin's lymphoma (NHL) in the United States also showed that older age was a risk factors for reduced RDI, in addition to lack of use of prophylactic colony stimulating factor (CSF), advanced disease stage, poor PS and a lower serum albumin level [19]. Here, CSF2 is linked to non-Hodgkin lymphoma.