VWF and endothelial dysfunction: We hypothesized that the relationship between inflammatory and hemostatic biomarkers including CRP, IL-6 plasma viscosity and several markers of activated coagulation, fibrinolysis and endothelial dysfunction [fibrinogen; coagulation factors VII, VIII, and IX; fibrin D-dimer, t-PA antigen, VWF activated partial thromboplastin time (APTT) and activated protein C (APC) ratio] differed between older men aged 60–79 years who develop (i) incident MI or CHD death and (ii) incident stable angina, uncomplicated by MI or CHD death.