Immunostaining of 51 of the 52 effusions (one unsatisfactory reaction) and 27 primary carcinomas showed significantly higher p-Ezrin expression in effusions compared to primary carcinomas (P < .001 in analysis of all cases, as well as patient-matched specimens), as evidenced by score = 4 staining in 49/51 effusions and only 2/27 primary carcinomas (Figures 4(c)–4(e)). Here, EZR is linked to carcinoma.