NOTCH4 and psoriasis: The SNP rs2073048 is located within the 4th intron of an open reading frame C6orf10, 27 kb telemetric to BTNL2 and 144 kb centromeric to NOTCH4. There have been previous reports of association of psoriasis with AGER, which is 183 kb telomeric of rs2073048, and with HLA-DRB1 that is 211 kb centromeric of rs2073048.