In this study, 22% of patients diagnosed with LPA (2/9) were found to have GRN mutations, which have been shown previously to be associated with asymmetrical hemispheric cortical atrophy frequently involving the parietal lobe (Beck et al., 2008; Rohrer et al., 2008b; Le Ber et al., 2008). Here, GRN is linked to Cerebral cortical atrophy.