CRP is influenced by modifiable risk factors such as body mass index, exogenous estrogen, diabetes, hypertension, smoking, alcohol use, HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A) reductase inhibitors, aspirin use, physical activity, LDL, and HDL (Cushman et al. 1999; Ridker et al. 1999). This evidence concerns the gene CRP and diabetes mellitus.