TP53 and neoplasm: In contrast, no significant difference in the frequency of p53-stained tumour cells could be detected when primary tumour biopsies (Mean±s.e.m.: 7.36±2.2%) and residual tumours were compared (Mean±s.e.m.: 7.50±4.4%) (mean diff=0.14, s.d.=14.2, P=0.965).