Edaravone was developed as an effective eliminator of the free radicals produced at the acute stage of cerebral infarction that would protect the ischaemic brain from oxidative damage.17 Thus, the mechanism of edaravone treatment is different from the conventional anticoagulant, platelet-aggregation inhibitor and anti-VEGF treatments used in cases of vascular blockage. This evidence concerns the gene VEGFA and cerebral infarction.