APMCF1 together with T-cell differentiation protein (MAL), diphosphoinositol polyphosphate phosphohydrolase type2 (NUDT4), plakophilin 4 (PKP4), and signal sequence receptor (SSR1) were the top five genes involved, which were highly up-regulated in short-term survivors compared with long-term survivors and early-stage cases of ovarian cancers [23]. This evidence concerns the gene PKP4 and ovarian cancer.