Our previous study showed that expressions of CCR2 and CD14 on monocytes in the blood of MS patients are markedly decreased, and revealed a significant negative correlation between CD4+CXCR3+/CD4+CCR4+ ratio and CCR2 and CD14 expressions on monocytes [Nakajima et al. 2004b]. Here, CCR4 is linked to myeloid sarcoma.