Chitotriosidase (ChT), is a human analogue of chitinases from non-vertebrate species that serves both as a diagnostic hallmark of Gaucher disease (GD, glucosylceramidosis), and as a marker for monitoring the efficacy of various therapeutic approaches for treatment of GD (Hollak et al. 1994, 2001; de Fost et al. 2006; Pastores and Barnett, 2005; Pastores et al. 2005). This evidence concerns the gene CHIT1 and Gaucher disease.