In this study, we used the area and intensity of CD34 positive sinusoid endothelial cells as a measurement of MVD and compared their value between normal liver and cirrhotic liver, between the non-neoplastic background liver adjacent to HCC-C (HCC-CB) and the non-neoplastic background liver adjacent to HCC-NC (HCC-NCB), and between the tumor tissue of HCC-C and HCC-NC. This evidence concerns the gene CD34 and neoplasm.