The association of high MVD-CD34 with high histological grade, the presence of lymphvascular space invasion, the presence of satellite lesions, high post-surgical tumor recurrence rate, high metastasis rate and poor disease-free survival has been observed in many studies (Tanigawa et al. 1997; El-Assal et al. 1998; Sun et al. 1999; Poon et al. 2002; Zhang et al. 2006; Yamamoto et al. 1998; Yao et al. 2005). This evidence concerns the gene CD34 and neoplasm.