In TCC an insoluble matrix form of FN was found along the urothelian tissue, but studies revealed diverse results of FN expression in bladder cancer tissue (Kirkali et al. 2001; Sanchez-Carbayo, 2000; Cheng et al. 1988; Zhang et al. 2004; Fleischmann et al. 1993). The gene discussed is FN1; the disease is urinary bladder carcinoma.