Several genes responsible for rare Mendelian forms of hypertension have been identified (CYP11B1, CYP11B2, HSD11B1, MR, SCNN1B, SCNN1G, WNK1, WNK4) and shown to play a significant role in the renal control of BP [3]–[9]. Here, CYP11B2 is linked to Hypertension.