CD4 and secondary progressive multiple sclerosis: PBMCs from healthy donors showed 28664 (mean value) IL-7R molecules on TCRαβ+CD4+CD25−CD107a+CD127+ T-cells, 50734 (mean value) molecules were observed on the same T-cell subset in PBMCs from patients with RRMS, 40634 (mean value) molecules were identified on TCRαβ+CD4+CD25−CD107a+CD127+ T-cells from individuals with SPMS and 36331 (mean value) molecules were enumerated on this T-cell subsets in PBMCs from patients with OND.