In contrast, the number of biologically relevant molecules, e.g. CD127, the alpha chain of the IL-7 receptor, on single cells has not yet been addressed: IL-7, signaling through the IL-7 receptor, has been shown to increase antigen-specific T-cell responses in patients with MS [6] and provide long-term T-cell survival and thymic output [7], which may lead to the expansion of auto-reactive T-cell clones [8]. The gene discussed is IL7R; the disease is myeloid sarcoma.