In contrast to the LPS-induced shock, we found no difference in survival and bacterial load in the spleen after i.v. challenge of wildtype and cIAP-1 KO mice with Salmonella Typhimurium SL1344 (Fig. S4), suggesting that additional mechanisms besides endotoxin exposure cause toxicity in the case of Salmonella infection. The gene discussed is BIRC2; the disease is Salmonella Infections.