IL6 and neoplasm: The serum IL-6 level was also correlated with metastasis (M1, 19.41 ± 23.79; M0, 4.62 ± 6.19, P = 0.0095), and it increased along with a higher tumor grade (grade 1, 3.82 ± 2.21; grade 2, 9.74 ± 4.41; grade 3, 12.08 ± 3.57, P = 0.0836) and higher stage (pT1–2, 4.88 ± 6.63; pT3–4, 14.54 ± 20.99, P = 0.0926).