PRKG1 and seminoma: We observed a promoting effect of BPA on seminoma cells through a rapid activation of cAMP-dependent protein kinase (PKA) and cGMP-dependent protein kinase (PKG) signaling pathways via a GPCR, illustrating that xenoestrogens, suspected to act as deleterious factors in breast and prostate cancers, could also act in this nongenomic pathway as possible promoting agents in testicular germ cell cancer.