KLK3 and androgenetic alopecia: Finasteride, a 5-alpha reductase enzyme-inhibitor that inhibits conversion of testosterone into active androgen metabolite dihydrotestosterone, thereby lowering prostate volume and serum prostate-specific antigen (PSA) level (Marberger, 2006), is used for treatment of benign prostatic hyperplasia (BPH) and male pattern baldness.