In the studies that assessed gene expression in a mixture of tumor cells and fibroblasts, we found three differentially expressed collagen genes: COL15A1, COL4A6, and COL4A5. All three were significantly downregulated; the corresponding P values were 7.8E-12, 7.0E-11, and 1.1E-9. The gene discussed is COL15A1; the disease is neoplasm.