BRCA2 and astrocytoma (excluding glioblastoma): Considering that: 1) BCCIP interacts with BRCA2 and p21, 2) BCCIP plays a role in homologous recombination, cell cycle regulation, p53 transcription activity, and chromosome instability [19-24,26,27], 3) BCCIP expression is absent in a significant portion of astrocytomas (Figure 2), and 4) the lack of BCCIP expression is correlated with the aggressiveness of astrocytomas (Figure 3), we suggest that BCCIP is a strong candidate for the tumor suppressor gene in the chromosome 10q26 region.