The multivariable adjusted odds ratios (95% confidence interval) for PAD associated with a two-fold increase in serum ferritin and transferrin saturation were 1.18 (1.00-1.41) and 1.45 (0.83-2.51), respectively, for men and 1.04 (0.87-1.25) and 1.55 (0.98-2.45), respectively, for women. The gene discussed is TF; the disease is peripheral arterial disease.