NFKB1 and cystic fibrosis: Because many pro-inflammatory genes are regulated by NF-kB, and since the latter has been implicated in the hyperinflammatory phenotype of CF epithelial cells, we examined NF-kB (p65) binding to its DNA consensus site in nuclear extracts obtained from Cftr+/+ and Cftr−/− diaphragmatic myotubes.