PRDX2 and sickle cell disease: Other transcripts that were identified to be differentially regulated in sickle cell disease included BMP2 kinase, selenium binding protein, exportin, spermine oxidase, peroxiredoxin 2, chemokines, interleukin receptor and peptidyl arginine deaminase and these are known to be key regulators in redox metabolism and inflammatory processes as shown in Table 3.