MAOB and cocaine dependence: A placebo-controlled, double-blind treatment trial using selegiline 10 mg per day orally for eight weeks (a dose in the range selective for MAO-B) suggested selegiline may be useful for the treatment of cocaine dependence, based on decreases in quantitative urine concentrations of the metabolite (benzoylecgonine) and improved self- and investigator-rated global clinical status (prepublication data, NIDA-MDD).