MAPK1 and hypertrophic cardiomyopathy: We found that at one day of age, the hypertrophic cardiomyopathy in OMDM and the dilated cardiomyopathy in OSDM was associated with limited changes in MAPK activation, although small changes were found at NB1 in OSDM in total ERK and active (phosphorylated) JNK (Figures 1 and 2).