This observation prompted us to investigate the potential for invasiveness and brain metastasis of KCNMA1 expression in normal breast cells (MCF-10A), non-metastatic breast cancer (MCF-7), non-brain metastatic breast cancer cells (MDA-MB-231), and brain specific metastatic breast cancer cells (MDA-MB-361). This evidence concerns the gene KCNMA1 and breast cancer.