The aim of our work was to find if MCP-1 -2518 (A/G) single nucleotide polymorphism (SNP) influences somehow the tested concentrations of hsCRP both in patients suffering from ischemic heart disease (IHD), myocardial infarction (MI), angina pectoris (AP), and hypertension (HT) within the cohort of IHD patients and in control group of healthy subjects. The gene discussed is CCL2; the disease is myocardial ischemia.