In AD patients below 10 years old (Group 1) a positive correlation between eosinophilia and CCL-20 (r = 0.53, P = .009) and IL-18 (r = 0.45, P = .03) was noted while in Group 2 eosinophilia correlated positively with CCL-27 (r = 0.52, P = .03). This evidence concerns the gene CCL20 and Alzheimer disease.