F2 and Cirrhosis: Among laboratory and sonographic parameters, variables significantly associated with mortality are PT difference between patient and control of ≥5 s (P < 0.001), AST: ALT ≥2:1 (P = 0.003), total bilirubin ≥4 mg/dL (P = 0.004), discriminant function score >32 (P < 0.001), ESR ≥34 (P = 0.005) and sonographic evidence of cirrhosis (P = 0.001) during the study and follow-up period.