The absolute value of AST and ALT in ALD patients is usually <300 u/L.[14] The diagnosis of ALD increases as the AST/ALT ratio increases.[15, 16] AST/ALT ratio >2 is suggestive of alcoholic hepatitis.[15] A high AST/ALT ratio also suggests advanced ALD.[10] Our study showed that AST/ALT ≥ 2:1 at presentation is significantly associated with increased mortality, with a P-value of 0.003. The gene discussed is GPT; the disease is alcoholic hepatitis.