In the pathogenesis of BL, the data suggest that EBV, through the action of EBNA3A and EBNA3C, is operationally equivalent to codon 57/58 mutants of Myc, since in infected cells induction of Bim by Myc would be inhibited and Bim levels kept very low. The gene discussed is BCL2L11; the disease is Burkitt lymphoma.