SUI Interstitial cystitis or BOO UTI during run-in period Recent electrostimulation or bladder training therapy Pregnancy, lactation, or failure by women of childbearing age to use reliable contraception Allergy to tolterodine Use of CYP3A4 inhibitors Treatment within 2 weeks of study with OAB therapy or anticholinergic drugs. This evidence concerns the gene CYP3A4 and interstitial cystitis.