ERBB2 and neoplasm: Patients' median age was 54 years (range, 26–75 years), 78 (47.3%) were pre-menopausal, (111) 91.5% had tumours >2 cm, 64 (38.8%) were of histological grade 3, 64 (38.8%) were ER negative, 33 (20%) were HER2 positive, and 106 (64.3) had infiltrated axillary lymph nodes.