LEP and Barrett esophagus: In regard to the circulating factors secreted from adipose tissue, while the serum adiponectin level was significantly lower in the group with BE than in the group without BE (p = 0.0089), the serum leptin level tended to be higher in the group with BE than in that without BE, although the difference did not reach statistical significance (p = 0.5058) (Table 2).