While a Latency I infection appears to provide low level protection from apoptotic triggers, the broadening of viral antigen expression in Wp-restricted latency BLs to include the viral Bcl2 homolog, BHRF1, and the EBNA3 family of proteins is associated with much stronger protection from apoptosis and a complementation of c-myc induced lymphomagenesis [27,59,112]. Here, BCL2 is linked to infection.