In 2008, Nguyen et al. found that high correlations between the primary tumours and metastatic lymph nodes in non-small-cell lung cancer patients and the GLUT1 mediated fluorodeoxyglucose (FDG) uptake may be useful for mediastinal lymph nodes discrimination by fluorodeoxyglucose positron emission tomography (FDG-PET). This evidence concerns the gene SLC2A1 and non-small cell lung carcinoma.