Similarly for block 1 and 2, ATCTGG or ACCCXX haplotype-pairs that contained TCT or CCC of TNF-α-1031 T/C, TNF-α-863 C/A and TNF-α-857 C/T were also associated with a significantly higher risk for gastric cancer only among smokers (OR = 3.1, 95% CI 1.0–10.0 for ATCTGG; OR = 4.7, 95% CI 1.2–18.2 for ACCCXX). Here, TNF is linked to gastric cancer.