For instance, in the cancer data after filtering, two validated exons were already found among the top ten detections with PECA-SI (ACTN1 probeset 3569830 rank 1, COL6A3 probeset 2605390 rank 7), whereas the best-ranking validated exon was ranked 28th with RMA-SI (ACTN1 probeset 3569830), 35th with PLIER-SI (CALD1 probeset 3025632), 50th with RMA-LM (MAST2 probeset 2334499), 82nd with PLIER-LM (MAST2 probeset 2334499), and 26th with FIRMA (ACTN1 probeset 3569830). The gene discussed is MAST2; the disease is cancer.