JAK1 and classic Hodgkin lymphoma: Therefore, we analysed the effects of the HSP90-inhibitor 17-AAG as well as RNA-interference mediated inhibition of HSP90 on the tyrosine phosphorylation of STAT1, STAT3, STAT5, STAT6 and protein expression of Jak1, Jak2, Jak3 and Tyk2 in cHL cells.