Increased expression of Wnt-5a, a hallmark of oncogenesis, was identified in melanoma skin cancer (Da Forno et al, 2008), breast cancer cells (Fernandez-Cobo et al, 2007), gastric cancer (Kurayoshi et al, 2006), pancreatic cancer (Ripka et al, 2007), non-small-cell lung cancer (Huang et al, 2005) and prostate cancer (Wang et al, 2007). This evidence concerns the gene WNT5A and familial pancreatic carcinoma.