WNT5A and familial pancreatic carcinoma: A cancer-promoting function was also shown in UACC 1273 melanoma cancer cells (Weeraratna et al, 2002), MKN-74 and MKN-45 gastric cancer cells (Kurayoshi et al, 2006) and in PANC1, HT1080, ImimPc1 and MiaPaca pancreatic cancer cell lines (Ripka et al, 2007), where overexpression of Wnt-5a promoted cell proliferation and invasion.