ALCAM and neoplasm: In addition, increased (Tomita et al, 2003; Weichert et al, 2004; Kristiansen et al, 2005; Verma et al, 2005; Burkhardt et al, 2006) as well as reduced (King et al, 2004; Mezzanzanica et al, 2008) expression of ALCAM has been correlated with poor prognosis, depending on the tumour type.