CD44 and ovarian serous carcinoma: Sillanpaa et al, (2003) reported that CD44 expression is related to well-differentiated, early-stage EOC and long survival of the patients, thus indicating a favourable prognosis in EOC. Kayastha et al reported that expression of CD44 is an independent predictor of survival in women with EOC. Afify et al (2006) reported that the expression of CD44s and CD44v5 is more common in stage III than in stage I serous ovarian carcinomas and suggested a role for CD44 and stromal HA in the dissemination of EOC.