Induction of CD44 expression has been noted during the development of EOC, but the issues of whether a high CD44 expression represents a relatively favourable prognosis (Ross et al, 2001) or an aggressive behaviour of the tumour and unfavourable prognosis (Kayastha et al, 1999), and whether CD44 has any prognostic significance (Berner et al, 2000), have remained controversial. Here, CD44 is linked to neoplasm.