Table 4 summarises the correlation among uPA, CD44 and MDR1 expressions in primary tumours with tumour grade, clinical stage, histological type, residual tumour after first surgery, relapse and ascites. The overexpression (HEG) of uPA, CD44 and MDR1 was correlated with relapse (P<0.01) and increased with the progression of EOC (tumour grade, P<0.01; clinical stage, P<0.05; residual tumour after first surgery, P<0.05; ascites, P<0.05). The gene discussed is CD44; the disease is neoplasm.