The reliability and acceptability of DL in 69 women at high risk of breast cancer due to Gail Model score ≥ l.66 (n = 38), a family history of breast cancer (n = 53), the presence of a BRCA1/2 (n = 2), a personal history of abnormal breast biopsies (atypical hyperplasia, non-invasive or invasive breast cancer, n = 20) or a prior history of breast cancer (DCIS/invasive breast cancer, n = 11) was found to be less than ideal [13]. The gene discussed is BRCA1; the disease is ductal breast carcinoma in situ.