Using cultures of human bladder carcinoma T24 cells in conjunction with terephthalic acid, a potent tumor promoter that induces ornithine decarboxylase (ODC), saliniketals were found to inhibit ODC induction with IC50 values of 1.95 and 7.83 μg/mL, respectively [45]. The gene discussed is ODC1; the disease is neoplasm.