The frequency of anaplastic versus any other histological subtype, or c-myc negative versus c-myc positive specimens in the MHC class I-high versus MHC class I-low or -negative medulloblastoma specimens is significantly different (Fig. 2), with p values being 0.0251 for histopathology (n = 105) and 0.0257 for c-myc expression (n = 88). Here, MYC is linked to medulloblastoma.