For example, meningioma 126M displayed amplification of an ~500 kb region (1.9–2.4 Mb) on chromosome 11 spanning, among other genes, the loci for insulin (INS) and insulin-like growth factor 2 (IGF2), which has been implicated previously in some meningiomas through expression studies [41]. The gene discussed is INS; the disease is meningioma.