For genetic traits, significant associations of interleukin (IL) -1B C-31T and C-511T polymorphisms [16,17], tumor necrosis factor (TNF)-α C-857T and T-1031C polymorphisms [18], and a NAD(P)H dehydrogenase, quinone 1 (NQO1) C609T polymorphism [19] with H. pylori infection, and associations of a G/A polymorphism at intron 2 of Grb2-associated binder 1 (Gab1) [20], interleukin (IL) 2 T-330G, and IL-13 C-1111T [21] with gastric atrophy have been reported to date. Here, TNF is linked to chronic atrophic gastritis.