These findings are consistent with experimental evidence suggesting a role for NF-κB in immunological and inflammatory diseases, cancer and therapy-resistance, in skeletal myogenesis and cachexia, as well as in cognition, behavior and neurological disorders like epilepsy, stroke, Alzheimer's, Parkinson's diseases, and amyotrophic lateral sclerosis (ALS) (reviewed in [76-79]). This evidence concerns the gene NFKB1 and nervous system disorder.