Immunohistochemical analyses revealed that 29/70 lung adenocarcinomas (41.4%), 22/49 of which were adenocarcinomas with bronchioloalveolar features (ADBF), 4/13 pure bronchioloalveolar carcinomas (BAC) and 3/8 conventional adenocarcinomas (ADC) [15], did not express IL-12Rβ2 (Table 1 and Fig. 1A, panel b). Here, IL12RB2 is linked to adenocarcinoma.