In contrast, basal-A lines appear mainly CD44+/CD24+, but express PROM1 (aka CD133), a marker of luminal progenitors in mice [86] also more recently characterized as a stem cell marker in BRCA1-associated breast cancer [87], while luminal lines express markers of luminal lineage restriction like GATA3 and FOXA1 [28]. This evidence concerns the gene BRCA1 and breast cancer.